Samarium-153 for bone pain
In a double-blind placebo-controlled trial in 118 patients with painful bone metastases, a single 1.0 mCi/kg dose of samarium-153 lexidronam relieved pain within a week, lasting to at least week 16 in most patients who responded.
As reported in: Serafini, Houston, Resche et al. (1998). Palliation of pain associated with metastatic bone cancer using samarium-153 lexidronam: a double-blind placebo-controlled clinical trial.. Journal of Clinical Oncology. doi:10.1200/jco.1998.16.4.1574
Abstract only