Selenium in glutathione peroxidase
Rotruck and colleagues showed selenium is part of glutathione peroxidase: red cells from selenium-deficient rats lacked the enzyme's activity and could not protect haemoglobin from oxidative damage, and the purified enzyme held much of the cells' radioactive selenium-75.
As reported in: Rotruck, Pope, Ganther et al. (1973). Selenium: Biochemical Role as a Component of Glutathione Peroxidase. Science. doi:10.1126/science.179.4073.588
Abstract only