Liver regeneration
Michalopoulos reviewed how the liver restores lost mass after partial removal using all its mature cell types.
As reported in: Michalopoulos (2007). Liver regeneration. Journal of Cellular Physiology. doi:10.1002/jcp.21172
Regeneration: basic research on living systems, not technology.
Also: hepatectomy, digit tip
Mammals regrow little, but the liver restores lost mass, and in mice the digit tip can regrow if the nail area remains.
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Michalopoulos reviewed how the liver restores lost mass after partial removal using all its mature cell types.
As reported in: Michalopoulos (2007). Liver regeneration. Journal of Cellular Physiology. doi:10.1002/jcp.21172
Takeo and colleagues showed in mice that Wnt activation in nail stem cells is needed for the digit tip to regrow; amputations below them fail to regenerate.
As reported in: Takeo, Chou, Sun et al. (2013). Wnt activation in nail epithelium couples nail growth to digit regeneration. Nature. doi:10.1038/nature12214