Artificial skin for burns
Burke, Yannas and colleagues successfully used a collagen-based artificial skin on patients with extensive burns.
Built / tested: artificial dermis
As reported in: BURKE, YANNAS, QUINBY et al. (1981). Successful Use of a Physiologically Acceptable Artificial Skin in the Treatment of Extensive Burn Injury. Annals of Surgery. doi:10.1097/00000658-198110000-00005
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Whole epidermis from gene-corrected stem cells
Hirsch and colleagues regrew most of a boy's skin using genetically corrected stem cells for the blistering disease epidermolysis bullosa.
Built / tested: transgenic epidermis grafts
As reported in: Hirsch, Rothoeft, Teig et al. (2017). Regeneration of the entire human epidermis using transgenic stem cells. Nature. doi:10.1038/nature24487
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