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Turritopsis "immortal" jellyfish

Experiments: basic research on living systems, not technology.

Also: Turritopsis dohrnii

A jellyfish that can turn back into a juvenile polyp after reaching adulthood.

Known properties: Turritopsis "immortal" jellyfish

Only what the cited papers report.

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Timeline

  1. 1996 Reversing the life cycle
  2. 2022 Genes behind rejuvenation

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lab biology 1996

Reversing the life cycle

Piraino and colleagues showed Turritopsis medusae at all stages can transform back into colonial polyps, the first animal known to revert after sexual maturity.

As reported in: Piraino, Boero, Aeschbach et al. (1996). Reversing the Life Cycle: Medusae Transforming into Polyps and Cell Transdifferentiation in <i>Turritopsis nutricula</i> (Cnidaria, Hydrozoa). The Biological Bulletin. doi:10.2307/1543022

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lab biology 2022

Genes behind rejuvenation

Pascual-Torner and colleagues compared genomes of T. dohrnii and a mortal relative and found expansions of genes for DNA repair, telomere maintenance and stem cells.

Publisher update notice: correction correction

As reported in: Pascual-Torner, Carrero, Pérez-Silva et al. (2022). Comparative genomics of mortal and immortal cnidarians unveils novel keys behind rejuvenation. Proceedings of the National Academy of Sciences. doi:10.1073/pnas.2118763119

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